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In recent years, liposomal technology has revolutionized the way nutrients and pharmaceuticals are delivered, enhancing absorption and bioavailability like never before. As consumer demand grows for more effective supplements and advanced drug delivery systems, U.S.-based manufacturers are leading the charge with cutting-edge liposomal innovations. This list highlights the Top 10 Liposomal Manufacturers in USA, each recognized for their scientific expertise, proprietary technologies, and commitment to quality.
Official Website: https://www.livonlabs.com/
Supplier Advantages:
Pioneered the use of liposomal technology in dietary supplements in 2004, utilizing patented nano-encapsulation to significantly enhance nutrient absorption.
Uses non-GMO soy lecithin to ensure high purity and formulation stability; all products are free from sugar, gluten, and artificial additives.
Employs single-serving sachet packaging for all products to prevent liposome degradation associated with multi-use containers.
Every formula is manufactured in cGMP-compliant facilities in the United States and tested by third-party labs to ensure purity and safety.
Recommended Products:
Lypo‑Spheric® Vitamin C (1000 mg): Offers superior absorption to support immune function, collagen synthesis, and antioxidant protection.
Lypo‑Spheric® Glutathione: A premier "master antioxidant" that supports liver detoxification and cellular health.
Lypo‑Spheric® B Complex Plus: Comprehensive support for energy metabolism and neurological function.
Video Introduction:
https://www.youtube.com/watch?v=xUL4ryHYRqU
Official Website: https://www.quicksilverscientific.com/
Supplier Advantages:
Since 2006, Quicksilver Scientific has specialized in liposomal vitamins and detoxification supplements, offering a mature product portfolio backed by scientific research.
Utilizes high-purity phospholipid encapsulation, with clinically validated formulations that deliver rapid and superior absorption, such as their brain-supporting Magtein® line.
Endorsed by over 30,000 healthcare practitioners and offering more than 60 liposomal formulas, demonstrating strong scientific and clinical credentials.
Recommended Products:
Liposomal Vitamin C (1000 mg): A liquid formula with enhanced bioavailability; gentle and easy to absorb.
Liposomal Glutathione: A leading detox and antioxidant supplement, with strong user feedback and effectiveness.
Liposomal Magtein®: A magnesium-based formulation designed specifically for brain health, supporting cognition and neurological function (as featured in their official product line).
Video Introduction:
https://www.youtube.com/watch?v=_UayLRXIabM
Website: https://purensm.com/
Supplier Advantages:
Specializes in large-scale liposomal liquids and powders—over 44 active ingredients—offering both hydrophobic and hydrophilic formulations in customizable bottle or sachet formats. Their GMP-compliant production and U.S.-based facilities enable fast lead times and private-label solutions.
Recommended Products:
Liposomal Apigenin 50 mg (capsules)
Liposomal CoQ10 100 mg
Liposomal NAD+ 250 mg
(All available as custom or stock products.)
Video Introduction:
https://www.youtube.com/watch?v=4XT5ZLn2e8g
Website: https://encapsula.com/
Supplier Advantages
Offers a broad portfolio of liposomal reagents for research and biotech/pharma—Clodrosome® (clodronate liposomes), Doxosome™ (doxorubicin liposomes), along with surface‑reactive, DNA/RNA, and fluorescent liposome kits. Tailored for academic and industrial R&D use.
Recommended Products:
Clodrosome® macrophage depletion reagent
Doxosome™ PEGylated doxorubicin liposomes
Encapsome® (control liposomes) and various fluorescent or nucleic acid‑laden liposomes
Video Introduction:
https://www.youtube.com/watch?v=EeAIapGSzJY
Website: https://smpnutra.com/
Supplier Advantages:
A full-service nutraceutical CDMO offering liposomal supplement manufacturing in a 155,000 sq ft FDA-registered GMP facility. Services include custom formulation, raw‑ingredient sourcing, packaging, and in-house marketing support. Trusted by brands sold in retailers such as Walmart, Target, and GNC.
Recommended Products:
Liposomal Vitamin D3 liquid with MCT oil, Bioperine®
Liposomal Chlorophyll liquid
Liposomal Irish Sea Moss blend, Biotin & Collagen liquid
Video Introduction:
https://www.youtube.com/watch?v=KLJGm-mUWNM
Website: https://avantiresearch.com/
Supplier Advantages:
Renowned for the highest purity research-grade lipids and advanced lipid formulations and delivery systems—including cationic lipids, PEGylated, fluorescent, and surface-modified vesicles. They support scalable drug delivery applications and liposome design from concept to commercialization.
Recommended Products:
Cationic lipids (e.g. DOTAP, GL67)
Custom PEGylated and fluorescent liposomes
Lipid prep kits for research-grade transfection and nanoparticle systems
Video Introduction:
https://www.youtube.com/watch?v=SAV4UlNr19I
Website: Provided via partner Cytiva (Precision NanoSystems, acquired by Cytiva)
Supplier Advantages: Specializes in scalable production of lipid nanoparticles and liposomes for RNA, mRNA, and siRNA therapeutics. Their proprietary NanoAssemblr platform enables repeatable, high-throughput nanoformulation.
Recommended Products:
NanoAssemblr™ BT / Spark / Ignite systems for liposome/RNA–LNP preparation
Kits and consumables for scalable lipid nanoparticle formulation
Video Introduction:
https://www.youtube.com/watch?v=QSII2XdPLA8
Website: https://integralbiosystems.com/
Supplier Advantages:
A CRO focusing on drug-delivery formulation R&D across administration routes (injectable, ophthalmic, intranasal, transdermal). Expertise includes liposomes, microspheres, hydrogels, and nano-complexes with fast turnaround and cGLP compliance.
Recommended Services:
Liposome-based drug delivery development (injectables, nasal, transdermal)
Analytical methods, formulation scale-up, IP strategy support
Video Introduction:
https://www.youtube.com/watch?v=QnrxUmnQCUM
Website: https://microfluidics-mpt.com/
Supplier Advantages: Developer of high-pressure Microfluidizer® systems that enable scalable, uniform nanoemulsions, liposomes, and nanoparticle production with exceptional process repeatability and yield, from milliliters to thousands of liters. Appropriate for biotech and pharma.
Recommended Equipment:
Microfluidizer® processors for microfluidic liposome encapsulation and nanoparticle processing
Video Introduction:
https://www.youtube.com/watch?v=VnvT2AlGycs
Website: https://cellg8.com/
Supplier Advantages:
Valimenta offers proprietary CELLg8® liposomal delivery technology—developed over 8 generations and decades of refinement—which encapsulates vitamins, minerals, and botanicals using a completely natural, solvent‑free, heat‑free, and pressure‑free process.
Recommended Liposomal Products
Valimenta's publicly available CELLg8®-based supplements offer enhanced absorption and clean formulations (free from gluten, dairy, sugar, and animal components):
Liposomal Vitamin C – clinically shown to raise blood levels significantly more than non-liposomal forms
Liposomal Zinc, Magnesium, Curcumin, Vitamin D3, CoQ10, Glutathione, B12, Sleep formula – available as stock or private-label products
Human clinical trials using CELLg8® formulations show up to 6× higher blood levels of B12, 73% higher vitamin D compared to regular supplements, and improved absorption of curcumin, green tea polyphenols, iron, ketones, and glutathione—with safety and efficacy validated in peer-reviewed studies.
Video Introduction:
